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WHO reported 2,501 new mpox cases, including 12 deaths, across 44 countries in October 2025. Africa saw 1,734 cases, with DRC, Liberia, Ghana, Kenya, and Uganda most affected. Clade Ib MPXV spread to Europe, the Americas, and Asia, with local transmission in Italy, Malaysia, the Netherlands, Portugal, Spain, and the US, while overall risk remains low.
